Vitamin D overview Dec 2009 

www.VitaminDWiki.com was opened April 2010
It has has far more information as well as user-generated content, blogs, forums, discussions, web news, etc.

- Table of contents -

Links      Diseases       Sunshine & UVB        Toxicity            Blood Tests        Books 

Life Extension Mag.    How much D3              Cod Liver        D2 problems

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I only learned about amazing benefits of vitamin D in mid Nov 2009 – took 4,000 IU daily for 2 weeks, then upped it to 5,000IU daily– and it has profoundly improved my health.
(Update Feb 2010: increased to 7,000 IU daily after finding that after 2.5 months that my blood level was only 44 ng/ml)

I suggest that you spend a few dollars for 30+ vitamin D capsules (5,000 IUs) and take them for a month.   Google Shopping has many for less than $4
I strongly believe that you will feel much better in that month and that will not have ANY side-effect. see dosing below

Be aware that many 1-a-day vitamins still use D2, rather than D3.  D2 is about 1/3 as affective as D3 in the body. more on D2 below

There is a 50 fold difference in the amount of vitamin D in pills  200IU to 10,000IU   many different ideas of how much vitamin D is needed
    An IU is a tiny amount: 10,000 IUs = 250 micrograms = 1/4 mg

Long list of medical problems which D3 probably will help you: See chart below and list

About 10 years ago a blood test for Vit D became available – and lots has been learned since then. See Blood Test below

In 2009 there were 821 trials of Vit D3  in the US which should conclude by 2012.

Vit D deficiency levels   >90% for fibro, elderly,   >60% blacks and newborn infants   >40% general Americans   this is based on the obsolete 20ng/ml definition for deficiency

Vitamin D Quotes are spread thru this webpage: a subset of quotes from the Vitamin D Council

Because vitamin D is so cheap and so clearly reduces all-cause mortality, I can say this with great certainty:
Vitamin D represents the single most cost-effective medical intervention in the United States.
     ~ Dr. Greg Plotnikoff, Medical Director, Penny George Institute for Health and Healing, Abbott Northwestern Hospital in Minneapolis.

This is like the Holy Grail of cancer medicine; vitamin D produced a drop in cancer rates greater than that for quitting smoking, or indeed any other countermeasure in existence.
    ~ Dennis Mangan, clinical laboratory scientist.

  • LINKS for vitamin D: articles, podcasts, videos

    Scientific American   Sunshine Vitamin  2007   my notes

    Wikipedia   Vitamin D deficiency

    Mercola Video  1 hour Fall 2008 with update in 2009.
    My notes: So new because only able to measure Vit D levels in the body since about 2000, 85% of people are Vit D deficient, UV provide Vit D – must get minimum pink, in winter cannot get ANY Vit D, 6X difference in absorption of Vit D by individuals – half of which is due to obesity

    Vitamin D from Linus Pauling Institute (which followed on Vitamin C)   updated Jan 2008

    GRC  has another vit D web page like this one. by Steve Gibson  last edited Oct 2009 (as of Dec 11, 2009) 
       click here for notes on his 1 hour podcast

    http://www.sunlightd.org/Main.htm

    http://www.vitamind3world.com/index.html  a commercial site with lots of information

    Vitamin D Society   Canadian Non-profit

    Dr. Mercola links for vitamin D   He authored a $17 book, Dark Deception  May 2008
        Amazon appears to only have the Kindle version of the book for $10

    Videos and audios at http://www.ucsd.tv/series/index.aspx?show=show&seriesnumber=520

    Vitamin D: Believe the Hype   great title of small article from the Chicagoist Dec 2009

    vitamin D Council   excellent, with lots of depth

    The Vitamin D Council also has over 100 links to abstracts on vitamin D deficiency

    Interview by One Radio Network by Dr. Cannell of Vitamin D Council 1 hour  Nov 2009  notes on interview are here
     here is the same interview 20% faster and with a little distortion - 1/2 the size to download

    http://www.msnbc.msn.com/id/28894095/ns/health-diet_and_nutrition/  MSNBC with some videos

    A decade of vitamin D supplementation would save the US $4.4 trillion.  May 2009 extrapolation of European study to the US, which had 25 pages

    Reducing the burden on Disease thru vitamin D   Grant, April 2008  powerpoint presentation

    Chochrane Library has 27 reviews involving vitamin D    
    Chochrane also lists 1473 clinical trials for Vitamin D (Dec 2009)
    Note: Cochrane tends to be extremely conservative: they will probably only look at vitamin D supplementation of < 1,000 IUs, or D2
       example  Interventions for preventing falls in older people living in the community

     You may be asking yourself: Is this vitamin C revisited?  Vitamin D seems to cure so many things. 
    One author states it nicely:
    Looking at that long list of problems above, you may wonder how something, anything, could possibly “cure” all of those very different disease conditions.
    But that's thinking about Vitamin D backwards.
        Vitamin D doesn't “cure” anything.
    NONE of those things are supposed to go wrong in the first place.
    So Vitamin D simply allows our bodies to work the way they were designed to  . . .
    because our bodies were designed to have much more Vitamin D circulating through them than most indoor-living Westerners do today.

    A Brief History of Vitamin D and Cancer Prevention by Mohr, Feb 2008 includes such things as
    - some of the benefits of cod liver oil were destroyed by heat: this was later named vitamin A, the other was misnamed vitamin D (it was later found to be a hormone)
    - the US Navy noticed in 1936 that sailors with skin cancer had reduced incidence of other cancers

    Vitamin D Quotes

    Sunlight is more powerful than any drug; it is safe, effective, and available free of charge.
    If it could be patented, it would be hyped as the greatest medical breakthrough in history. It's that good.
        ~ Mike Adams, natural health researcher and author.

    Vitamin D is, without question, the miracle nutrient of the century.    ~ Mike Adams, natural health researcher and author.


    Vitamin D and diseases

    Vitamin D helps avoid many diseases and helps cure some diseases

    Vitamin D Council has many pages with research articles for vitamin D for each of the following diseases *Addison's Disease *Allergic Hypersensitivity *Alzheimer's *Ankylosing Spondylitis *Asthma *Autism Research *Autoimmune Illness *Benign Prostatic Hyperplasia *Bladder Cancer *Breast Cancer *Cancer *Celiac Disease *Cerebral Palsy *Chronic Obstructive Pulmonary Disease *Chronic Pain *Cognitive Function *Colon and Rectal Cancer *Depression and Seasonal Affective Disorder *Diabetes *Endometrial Cancer *Epilepsy *Eye Cancer *Gaucher's and Fabry's Disease *Graves' Disease *Hashimoto's Thyroiditis *Heart Disease *HIV and AIDS *Hypertension *Inflammatory Bowel Disease *Influenza *Liver Cancer *Liver Function Diseases *Lung Cancer *Lymphoid Cancer *Melanoma *Mineral Metabolism *Multiple Sclerosis *Muscular Weakness and Falls *Obesity *Osteoarthritis *Osteomalacia *Osteopenia *Osteoporosis *Otosclerosis *Ovarian Cancer *Pancreatic Cancer *Parathyroid Function *Parkinson's Disease *Pediatrics *Postmenopause *Pregnancy and Lactation *Premenstrual Syndrome *Prostate Cancer *Renal Function *Rickets *Sarcoidosis *Sickle Cell Disease *Skin Cancer *Stroke *Toxin and Radiation Exposure *Tuberculosis *Turner's Syndrome *Veterinary

    Garland: shows the results of many research trials.

    Rickets was just the top of the vitamin D iceberg : page 4 Vitamin D Prescription

    Vitamin D  Status of Evidence

    click here to get the document which has the above chart

    Vitamin D and Back Pain  Google: "vitamin d" "back pain" 780,000 hits

    http://mednar.com/mednar/resultList/fullRecord:back+pain+%22vitamin+d%22/ >1,000 hits seem to include vitamin D as well as the phrase "back pain"  My favorite health search engine

    Vitamin D and Neck Pain Google "vitamin d" "neck pain"   110,000 hits

    Vitamin D and Ovarian Cancer

    Discussion group

    Vitamin D and Psoriasis  Google: 400,000 hits for " Vitamin D" Psoriasis

    FDA has approved it as a prescription for external use on psoriasis. http://www.webmd.com/skin-problems-and-treatments/psoriasis/news/20090203/psoriasis-ointment-gets-fda-approval
    There is a web page where you can vote on home remedies for psoriasis.  Vit D is the most popular as of Dec 2009
    The psoriasis on one knee I have been medicating for the past decade went away within a few weeks of taking vitamin D.

    Vitamin D and Osteoporosis

    Many sources on this page show a strong reduction in the incidence of osteoporosis with large increases in vitamin D.
    A Sep 29, 2008, FDA ruling, effective Jan 1, 2010, would allow claims that supplemental vitamin D  may be of value in preventing osteoporosis.
       unfortunately the FDA allows any form of vitamin D, and allow any product containing just 80 IU of vitamin D to mention it.
         Since it was sponsored by the Coca–Cola Company, I expect that they are not able to put much more than 80 IUs into a beverage without changing its taste or increasing its cost.

    Vitamin D and Heart

    Millions of American Men at Undue Risk for a Heart Attack If a study of 18,225 American men (health professionals) age 40–75 years is reflective of the entire population of middle-aged males, three-quarters of adult males in the U.S. face a doubling of their risk for a heart attack due to low vitamin D levels. A vitamin D deficiency is far more predictive of a future heart attack than cholesterol, says a report due to be published in the Archives of Internal Medicine on Monday, June 9, 2008.

    Vitamin D increases the level of HDL, but not LDL  my clipping of 4 web items from Dec 2009 

    Vitamin D and Diabetes

    above chart is from

    Vitamin D and Obesity

    NephroPal Blog: Health from a Paleolithic Standpoint on Oct 2 2009 describes how Hormone D (vitamin D) increases the level of the hormone adiponectin

    Vitamin D and Multiple Sclerosis

    Sept 2008 by Garland

    Another chart summarizes the mountain of information on MS and vitamin D as of 2009

    Vitamin D and Lupus

    Example: 2009 paper on Lupus and Vitamin D in the blood

    Vitamin D decreases SAD?

    Lots of strong opinions.  Papers/statements by both sides.  Here is a tiny sampling
    July 2009 yes   March 2009 no   Jan 2009 yes   Wikipedia  Vitamin D Council  yes - about 50 papers  Personal account  yes

    Vitamin D increases Longevity

    http://findarticles.com/p/articles/mi_hb4345/is_3_36/ai_n29426710/   March 2008

    http://www.vitamindcouncil.org/science/research/vitamin-d-and-mortality.shtml  seems like over 100 links to abstracts on vitamin D reducing all-cause mortality

    Richards et al (2007) found that, the higher the vitamin D, the longer the telomere length.
    The highest vitamin D levels conferred a 5-year effective difference in telomere length.

    above chart is from

    Vitamin D and Fatigue

    http://www.fightingfatigue.org/?p=1220  The Dangers of Vitamin D Deficiency  with 1600 comments, 50,000 IU once per week   D2 / D3?

    The Fibromyalgia Vitamin D Discussion Group, at MDJunction

    Vitamin D and Autism

    Dr. Cannell of Vitamin D Council has a widely published hypothesis of the correlation and a set of articles
    Life Extension Magazine has a long article discussing that correlation

    Vitamin D and Leaky Gut

    http://nephropal.blogspot.com/2009/07/leaky-gut.html
    Inflammatory Bowel Diseases (IBD) such as Crohn's Disease and Ulcerative Colitis.
    Also discusses Celiac Disease and how NSAIDs increase problems of leaky guts


    Sunshine

    Cancer vs latitude

    from Ecological Studies Of Ultraviolet B, Vitamin D And Cancer Since 2000 published Ann Epidemiol 2009;19:446–454.

    Vitamin D-sensitive cancers with strong support after accounting for other factors:
    - Gastrointestinal: Colon, esophageal, gallbladder, gastric, pancreatic, rectal, small intestinal
    - Urogenital: Bladder, kidney, prostate
    - Female: Breast, endometrial, ovarian
    - Blood: Hodgkin’s lymphoma, non-Hodgkin’s lymphoma

    In multi-factorial ecological studies of cancer mortality rates in the United States, we found:
    - UVB: inverse for 14 types of cancer1
    - Air pollution (PAH with black carbon): 13 types 2
    - Smoking: risk for 10 types 1
    - Alcohol: risk for 9 types 1
    - Hispanic heritage: risk for 3 types 1
    - Latitude: primary risk for 1 type (prostate) and important for 1 type (Hodgkin’s lymphoma) 3
       1. Grant and Garland, Anticancer Research, 2006
       2. Grant, in review;
       3. Grant, Photochem Photobiol. 2008

    Decreased UVB was found to be more strongly correlated with lung cancer than was cigarette consumption in 111 countries.
    Study published  Jan 2008   http://www.ncbi.nlm.nih.gov/pubmed/18079336

    Annual UVB intensity    from Solar ultraviolet-B exposure and cancer incidence and mortality in the United States, 1993–2002

    Vitamin D totally blocked by Sunscreens

    UV/Sunlight/Sunscreen   About 1/2 of the sunscreens block the UVB which makes the D3 in your skin and tan, while letting through the more powerful UVA which can cause skin cancer
    Natural limit on amount of Vit D from the sun – no need to stay in the sun for more than 15 minutes in the summer
    Various sunscreens allow thru too much UVA and let people think that they can stay in the sun much longer.

    UVB sunscreen probably increase melanoma for people using it a latitudes higher than 40 degrees http://www.ncbi.nlm.nih.gov/pubmed/18022535?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=14


    Vitamin D and UVB

    The following chart shows how much UVB changes with season and clouds. 
    Virtually impossible for a senior citizen to get enough UV in Northern latitudes on cloudy, winter days.

    Click here for UV index for you state in the US

    This map of the world shows how little UVB gets to the Northern latitudes in Winter

    http://www.vitamindcouncil.org/researchUV.shtml  appears to have over 100 links to research abstracts on UV and vitamin D

    Interesting to note: There are many low cost UVB bulbs and lamps for pet reptiles.  They need UVB and we do not?
    Google Product Search

    Nice web page on how much UVB gets thru glass, trees, plastic, etc  a resource for reptile owners

    WikiPedia on UV has the following definition of the bands
    UVA or black light 400 nm–315 nm;   Near NUV 400 nm–315 nm;   UVB 315 nm–280 nm,    Middle MUV 300 nm–200 nm;   UVC 280 nm–100 nm

    One of the many UV calculators on the web gives much more precise analysis
       does not consider age nor clothes but adds type of ground and altitude

    There are many UV meters which cost less than $20  unsure what light spectrum they measure
        the UV Hawk displays the remaining number of minutes of tanning for your skin color and sunscreen SPF with UV that it measures in 2 seconds  many suppliers

     One $200 meter is calibrated in IUs

    Showering within 48 hours removes some vitamin D from the skin   Mercola May 12 2009


    So, how long do I need to be in the sun?

    A young Caucasian on the equator can get enough vitamin D from sunshine on the beach in 3 minutes.

    As a very rough approximation you need to increase by 3X for each of the following:

    cloudy senior dark skin high latitude winter lots of clothes sun screen

     Example for myself:
       Time in the sun = 3 minutes  * 3 (cloudy) * 3 Senior * 3 (high latitude) * 3 (winter) * 3 (lots of clothes)
                                 =  3 minutes * 15 = 45 minutes every cloudy winter day

         Please remember: 3X is just an approximation.    Each factor may be lower than 1.5X or higher than 10X


    Vitamin D Toxicity

    http://www.vitamindcouncil.org/vitaminDToxicity.shtml  Side Effects: “If there is published evidence of toxicity in adults from an intake of 250 ug (10,000 IU) per day, and that is verified by the 25(OH)D concentration, I have yet to find it."  .  Also has a section Cholecalciferol (D3), Not Ergocalciferol (D2), Is Safe

    Toxicity and overdose have been related to vitamin D2 intake but not D3 intake.  Doses of more than 50,000 IU daily of vitamin D2 were associated with high calcium and low phosphorous levels in the blood whereas doses up to 10,000 IU daily of D3 for 5 months do not cause toxicity.  http://blogs.webmd.com/cholesterol-management/2008/12/vitamin-d-deficiency.html

    Garland  too much Vit D  http://www.empowher.com/media/video/video-dr-cedric-garland-are-there-negative-side-effects-associated-excess-vitamin-d

    “We have to be careful, because we’re sort of in a grey zone here,” he said. “We know that people really need a higher vitamin D nutritional status than they have, but they can’t go bonkers. Presently the government says that the upper safe level is 10,000 IU a day. The vitamin D community … would say that probably could go up to 50,000 and maybe even 100,000 IU.”  link  Jan 2009


    From Garland - toxicity


    Only 1 research paper showed toxicity at 10,000 IUs per day, and many showed now problems with 30,000 IUs per day

    Another chart on toxicity from grassroots

    You might also be interested in section: Supplements and Side Effects


    Vitamin D Blood Tests

    Click here for Google Search   examples from Dec 2009 follow:

    http://www.vitamind3world.com/Vit_D_blood_test.html  $70  home test kit  Vitamin D3 World

    http://www.integrativepsychiatry.net/vitamin_d_25hydroxy_.html   $69

    http://www.privatemdlabs.com/lp/Vitamin_D_25-Hydroxy.php  $59

    http://www.personalabs.com/60-Test-Detail-Vitamin-D-25-hydroxy-vitamin-D.aspx  $60

    Life Extension Force  $47 for members (I am a member), $63 for non-members   they have occasional sales.

    Vitamin D Action: is an international public health project which sponsors a $40 blood test for its members (free to join?)
         most of the blood they have tested showed less than 40 ng/ml

           Based on the graphs of response to oral vitamin D below, I have decided to wait for 2 months after increased vitamin D to get my own blood tested


    Books which I own

    Vitamin D Cure May 2009 by James Dowd     Amazon allows you to search the text inside of the $10 book
    Musculoskeletal pain: 93% with patients with unexplained widespread pain had vitamin D deficiency Mayo Clinic pg 12
    Cheese produces 20 points of acid per serving. 2X to 3X more than other protein sources. Dowd calls cheese the king of junk foods. Pg 23
    Magnesium deficient: more than half of the people who are deficient in vitamin D. Need to increase it as well as vitamin D, but no easy way to test it. Pg 38
    Dowd had good results of vitamin D supplementation for fibromyalgia pg 40
    Chart of D3 dosage to get to 60 ng/ml
    on page 49
        if at 20 ng/ml, dose 30 IU/lb; if 10 ng/ml then dose at 38 IU/lb, if at 30ng/ml then dose at 23 IU/lb
    discusses a great many diseases
      the website for the book   his blog   his recommendation of supplementation (e.g. Ca, Mn, Omega-3, ...)

      

     

     

    Vitamin D Prescription  May 2009 by Eric Madrid  
    Amazon allows you to search the text inside of this $15 book  14 ***** reviews
    also available in Kindle format at lower cost
     Author's posts in wellsphere    website for the book

     

     

     

     

     

    UV Advantage  paperback version of 2003 hardcover 
    by M Holick - pioneer in vitamin D and author of many papers and books
     Amazon    11 ***** customer reviews    web site for the book, Vitamin D Health.org, UV Foundation

    Authored Vitamin D Deficiency article in New England Journal of Med Jul 19, 2007

    In studies in Saudi Arabia, the United Arab Emirates, Australia, Turkey, India, and Lebanon,
    30 to 50% of children and adults had 25-hydroxyvitamin D levels under 20 ng/ml

    52% of Hispanic and black adolescents in a study in Boston23 and 48% of white preadolescent girls in a study in Maine24 had 25-hydroxyvitamin D levels below 20 ng/ml.
    In other studies, at the end of the winter, 42% of 15- to 49-year-old black girls and women throughout the United States had 25-hydroxyvitamin D levels below 20 ng/ml

    One study showed that 93% of persons 10 to 65 years of age who were admitted to a hospital emergency department with muscle aches and bone pain and who had a wide variety of diagnoses, including fibromyalgia, chronic fatigue syndrome, and depression, were deficient in vitamin D.

    His lab (pg 149) studied the amount of vitamin D actually in milk (should be 100 IU): most had less than 20IU, half less than 50IU, and 14% had no detectable vitamin D
    Oil on the skin increases the amount of vitamin D produced - probably by decreasing reflectivity  pg 157
    The skin produces beta endorphins along with vitamin D (pg 24). That is why it feel so good.

    The Healing Power of Sunlight and Vitamin D ( free downloadable PDF) interview of  Holick   2005 Interview by Mike Adams  17 pages

    Vit D article in 2009 Journal of American Physicians and Surgeons   click here for some highlights

    Vitamin D Quote    We estimate that vitamin D deficiency is the most common medical condition in the world.
        ~
    Dr. Michael F. Holick, Vitamin D expert.


    Sunshine and Vitamin D: Frank Murray   can search inside of the book at Amazon
    Sept 2008      1 ***** review
     

     

     

     

     


    Vitamin D3 and Solar Power for Optimal Health,  Marc Sorenson, 2nd edition  2008
    Amazon   $20    1 **** of new edition
    website for book = http://www.vitaminddoc.com
    from his website:
    Dr. Sorenson and his wife, Vicki, developed one of the top health resorts in the world, known as National Institute of Fitness (NIF). 
    During their time at NIF their clients lost over one hundred tons of fat.  
    His fitness accomplishments include: 1. State Open Weightlifting Champion. 2. Winner of several racquetball tournaments, including World Senior Games Champion. 3. Marathon finisher 4. Pedaled bicycle from Phoenix, AZ to Fairbanks, AK (4000 miles). 5. He twice bicycled from the beach on Maui, Hawaii to the top of Mt. Haleakala—a distance of 38 miles and a climb of 10,000 feet. 6. Has walked, jogged and cycled the equivalent of more than 40,000 walking miles.


     

     

     


    M Holick also edited professional book on Vitamin D  Amazon $174  1999
    2nd edition is due out April 2010 1048 pages $246

    He will be authoring a new book for the lay public in April 2010   $17
    Which I will probably buy.
     

     

     

     

     

     

     

     

    One person, Rich Blumenthal, seems to have posted detailed reviews of many Vitamin D books on Amazon


    Shockingly Low Vitamin D Levels in Life Extension Members
         Jan 2010 issue of Life Extension Magazine featured article  

    ”No other nutrient, drug, or hormone has gained more scientific credibility than vitamin D.”

    Some interesting items in the article include:
    - as people age they over-react to virus - but vit D down-regulates that reaction
    - LEF is now recommending D level in blood of 50 ng/ml

    - 87% of the 14,000 Life Extension members who had their vit D blood levels tested from March 08-Sept 09 had less than 50 ng/ml
    - Vitamin D council is recommending  between 4,600 IUs and 10,000 IUs daily - and has strong evidence that 10,000 IUs is not toxic
    - Cod Liver oil now has more vit A and less vit D than it did 80 years ago (farmed fish?)
        and since vit A is an antagonist for vit D (both fat soluable) a person may end up actually decreasing vit D in the blood by taking modern cod liver oil
    - One study showed that taking preformed vitamin A (not beta-carotine) resulted in 2.1X MORE hip fractures, and INCREASED overall mortality by 16%.
    - LEF is increasing the D3 in their mix from 1,000 IUs to 2,000 IUs and recommends that everyone take an additional 5,000 IUs daily in the winter

    Life Extension Foundation had a previous article on vitamin D deficiency
        Sept 2007 "Should the President Declare a National Emergency which had 175 references


    Vitamin D  how much to take

    following two blue charts are from grassroots


    Notice that the vertical axis is in nmol/Liter.  the conversion is 100 nmol/L = 40 ng/ml
    So it appears that taking 5,000 IU should result in 60 ng/ml blood level after 2 months.

    Grassroots also has a chart that shows that the blood level is able to adapt to even (a single?) 100,000 US dosing
    Note: the vertical access on the following chart is change in units of nmol/Liter  from a baseline of  about 30 ng/ml
         to get ng/ml, divide by 2.5
    So the chart appears to say, that starting with a baseline of 30 ng/ml and taking 100,000 IU (single day?)  that the blood level spikes above 40 ng/ml,
        but returns to just above 30 ng/ml after 4 months.

    New Zealand study giving 4,000 IUs to women raised median vitamin D blood levels from 21ng/ml up to 74 ng/ml

    Dr. Davis on his Heart scan blog is aiming for 60-70 ng/ml as of Nov 2009

    Heart Scan blog on March 27, 2009 mentions a Toronto study that found  a 3 to 1 range between individuals in vitamin D level in blood for taking 4,000 IUs of vitamin D

    Heart Scan Blog  Feb 15, 2009 doctor prefers gelcaps: "gelcaps never fail; tablets fail over 80% of the time"

    Heart Scan Blog Feb 15, 2009  The requirement for vitamin D... ranges from as low as 1000 units per day to as high as 20,000 units per day...
    Being a hormone--not a vitamin, as it was incorrectly labeled--vitamin D needs to be tightly regulated. ...I would liken it to thyroid hormones, which need to be tightly regulated for ideal health.
     It is impossible to state that all men or women, categorized by age, require X units vitamin D. This is pure folly and it is misleading.

    http://nephropal.blogspot.com/2009/09/vitamin-d-and-office-observations.html 
    - Vitamin D taken at night causes insomnia.
    - Softgels are more effective than tablet form

    http://www.grassrootshealth.net/media/download/20091103veith.pdf 
    Rule of thumb: each additional vitamin D3 intake of 1,000 IU/d raises 25(OH)D by about 10 ng/ml

    Following chart from Garland recommends 60 ng/ml

     

    Vitamin D Action:  seems to recommend 40 ng/ml

     

    Supplements and side effects

    From Vitamin D Cure

    Probably need Magnesium if get muscle cramps after taking extra vitamin D   Vit D Council Newsletter July 2009

    http://www.easy-immune-health.com/Vitamin-D-Side-Effects.html 

    Mayo Clinic: SIDE EFFECTS: This medication is generally well tolerated. Notify your doctor if you experience: nausea, loss of appetite, vomiting, stomach cramps, dry mouth, increased thirst, increased urination, muscle or bone pain, headache, weakness, weight loss, dizziness. If you notice other effects not listed above, contact your doctor or pharmacist.

    From 2006 - > 50,000 IU perhaps D2 instead of D3

    Overdose symptoms in categories: within weeks, within months, etc.  
        He is taking 4,000 IU and having mild overdose symptoms. Extensive discussion with lots of comments

    Vitamin D Quotes

    I would challenge anyone to find an area or nutrient or any factor that has such consistent anti-cancer benefits as vitamin D.
    The data are really quite remarkable. ~
    Dr. Edward Giovannucci, Vitamin D expert.

  • Whoever wishes to investigate medicine properly should proceed thus:  in the first place to consider the seasons of the year.
        ~ Hippocrates, the father of medicine (circa 400 B.C.).


    Cod Liver Oil Controversy

    Rickets – was the tip of the vitamin D iceberg  in the 1930’s.  US children were taking cod liver oil in the 30's
    However: Cod Liver oil now, 70 years later, seems to have more Vit A and less vitamin D than it did before.  Also:
    Mercola says to avoid taking cod liver oil  Says there is no vit A deficiency, and that 5% have vit A toxicity, and that vit A increases infections

    Vitamin D2 vs D3

    Controversy: too much vitamin D2 and Vitamin D3

    7 reasons to take vitamin D3 instead of D2

    Vitamin D2 belongs in the garbage

    click to toxicity section of this web page

    Heart Scan Blog Sept 2, 2009 on why vitamin D2 should not be taken 
    On drug company even has brand named their D2 as " Maximum D3"
    Should never use a plant-form of a hormone (D2) when an animal form (D3) is available.

    Heart Scan Blog Aug 11 2009 D2 does not last as long in the body
    Also, as we age, the ability to metabolize D2 is dramatically reduced

    Henry Lahore   back to my home page   back to my supplements page

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